Antiplatelet drugs are prescribed to individuals with a history of heart attacks and these drugs aid in reducing reoccurrence of heart attacks. Some of the antiplatelet medications include, aspirin, clopidogrel, prasugrel, and ticagrelor. Aspirin is recommended for all patients with Acute Coronary Syndrome (ACS), in the absence of hypersensitivity. It is prescribed along with one of the oral antiplatelet agents including Clopidogrel, Prasugrel, and Ticagrelor. Prasugrel is prescribed for patients suffering from ACS and for those undergoing Percutaneous Coronary Intervention (PCI). Clopidogrel and Ticagrelor aid in preventing atherothrombotic events in adult patients with ACS, and those who are treated with Coronary Artery Bypass Grafting (CABG) or PCI.
The global antiplatelet drugs market size was valued at US$ 1.5 billion in 2017 and is expected to witness a CAGR of 7.6% over the forecast period (2018 – 2026).
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Increasing incidence of cardiovascular diseases is expected to drive growth of the antiplatelet drugs market
Increasing prevalence of cardiovascular disorders, growing geriatric population, and sedentary lifestyle are some of the major factors driving the global antiplatelet drugs market growth. Cardiovascular diseases are the principal cause of death in the developed and emerging economies. According to a report by Centers for Disease Control and Prevention (CDC), 2015, around 800,000 people in the U.S. die annually due to stroke and other cardiovascular diseases. Some of the common cardiovascular diseases include, rheumatic heart disease, hypertensive heart disease, inflammatory heart disease, ischemic heart disease, and cerebrovascular heart disease.
Antiplatelet Drugs Market - Regional Insights
On the basis of region, the global antiplatelet drugs market is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America and Europe antiplatelet drugs market are expected to foresee significant growth by 2026 as cardiovascular diseases are the principal cause of death in these regions. According to a European Heart Journal 2014 study, Coronary Heart Diseases (CHD), particularly Myocardial Infarction (MI), is responsible for around 1.8 million deaths in Europe, annually.
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Increasing prevalence of cardiovascular diseases in Asia Pacific is expected to fuel the antiplatelet market growth in the region. According to the American Heart Association, in 2011, 17,050 deaths among Asian and Pacific Islanders were due to cardiovascular diseases; 7,828 due to coronary heart disease; and 2,476 due to myocardial infarction.
However, according to the American Heart Journal 2015 data, people in Asia Pacific are susceptible to antithrombotics or fibrinolytics and to be associated with a higher bleeding risk during management of ischemic heart diseases and antithrombotic therapy. For instance, excessive bleeding risk with standard doses of new P2Y12 inhibitors is observed in patients in Asia Pacific, especially in its eastern region. According to the Circulation Journal 2014 report, for Prasugrel, a lower maintenance dose of 3.75 mg daily was used in clinical studies and approved for Japanese patients. The lower body weight of patients in Asia Pacific, fixed dose regimen of most antiplatelet drugs, and different genetic backgrounds are the potential factors responsible for increased risk of bleeding. Therefore, bleeding is viewed as a primary concern for selecting antiplatelet drugs for patients in Asia Pacific.
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Antiplatelet Drugs Market - Competitive Landscape
Key players operating in the global antiplatelet drugs market include, AstraZeneca Plc, Boehringer Ingelheim GmbH, Bristol-Myers Squibb Company, Daiichi Sankyo, Inc., Eli Lilly and Company, Merck & Co., Inc., Otsuka Pharmaceutical Company, Ltd., Sanofi, and The Medicines Company. Manufactures in the antiplatelet drugs market are focused on targeting either surface receptors or enzymes in the platelet in order to protect against unwanted clot formation following initial platelet activation.
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